The primary benefits of unweighing occur in a variety of physiological ways as outlined below.

• Symmetrical Loading of the Lower Extremities

This assists with equal weight distribution over the base of support. Equal weight distribution in turn provides the proper biomechanics to correct step length deficits and time distribution between limbs.

• Reduction of Muscular Splinting

Parasympathetic tones typically associated with neurological pathologies can be reduced through PWB therapy. Minimizing parasympathetic stimuli help to reduce muscular tension allowing for increased range of motion (ROM) and focus on motor control exercises.

• Reduction of Cardiovascular and Metabolic Demands

Relieving portions of body weight allow the patient to exercise with less stress to the cardiopulmonary system, beneficial for deconditioned patients as it allows them to initiate exercise without increasing cardiopulmonary demand. VO2 levels are maintained better at 40% unweighing than at 0%, the patient can then also exercise for a longer period. This application can be beneficial for cardiac and pulmonary rehabilitation.